Our latest work describing long-term plasticity at GABAergic synapses is now out at Neuron. This great work from former postdoc Chiayu Chiu shows that activation of NMDA-type glutamate receptors produces a long-term potentiation of inhibitory inputs arising from SOM-INs. Surprisingly, synapses from PV- and VIP-INs do not exhibit this plasticity. Our results suggest this difference is due to a diversity of postsynaptic molecular composition across somatic and dendritic GABAergic inputs. Thanks also to great collaborative effort from my colleagues Susumu Tomita at Yale and Steve Tavalin at U. Tennessee!
