News

May 14, 2018

New faces in the lab!

We’d love to welcome our new INP rotation student, Kathy Zhang, to the lab!  Kathy is particularly interested in state-dependent modulation of cortical circuits and will be carrying out a project imaging V1 activity in awake behaving mice.  In addition, we will have a number of Yale undergrads working with us this summer, Natasha Zaliznyak, Chika Ogbejesi, and Dawit Mengesha.  Shaping up to be a great summer!

 

April 30, 2018

Just got back from an awesome retreat for the Yale Department of Neuroscience at Jiminy Peak, MA! Great talks and a lot of fun had by all.  Thanks to Alka for another bottle of famous Polish vodka!  Here is a group pic of the current Higley and Cardin labs.

 

April 23, 2018

We’d like to welcome Dr. Jyoti Gupta, our newest postdoc, to the lab!  Jyoti did her graduate work with Dr. Jan Nagele at Wesleyan.  She will be studying the function of excitatory inputs to GABAergic interneurons in the mouse cortex.

 

January 19, 2018

Our latest work describing long-term plasticity at GABAergic synapses is now out at Neuron.  This great work from former postdoc Chiayu Chiu shows that activation of NMDA-type glutamate receptors produces a long-term potentiation of inhibitory inputs arising from SOM-INs.  Surprisingly, synapses from PV- and VIP-INs do not exhibit this plasticity.  Our results suggest this difference is due to a diversity of postsynaptic molecular composition across somatic and dendritic GABAergic inputs.  Thanks also to great collaborative effort from my colleagues Susumu Tomita at Yale and Steve Tavalin at U. Tennessee!

 

June 8, 2017

We are sad to say goodbye to postdoc Dr. Gyorgy Lur, who is starting his own group at the University of California, Irvine this summer.  Gyuri made fundamental contributions to the lab’s work understanding the regulation of synaptic transmission down to the level of single dendritic spines before branching out to pioneer our in vivo studies of mouse visual cortex.  We wish him all the best in his new endeavor!