New paper up at Neuron!

Our latest work describing long-term plasticity at GABAergic synapses is now out at Neuron.  This great work from former postdoc Chiayu Chiu shows that activation of NMDA-type glutamate receptors produces a long-term potentiation of inhibitory inputs arising from SOM-INs.  Surprisingly, synapses from PV- and VIP-INs do not exhibit this plasticity.  Our results suggest this difference is due to a diversity …

New rotation students!

We are excited to welcome new INP students Sachira Denagamage and Hyong Kim to the lab!  Sachira will be looking at the role of GABAergic interneurons in visual perception and Hyong will be studying the regulation of inhibitory synapses by mTOR.

Gyuri departs to start his own laboratory at UC Irvine!

We are sad to say goodbye to postdoc Gyorgy Lur, who is starting his own group at the University of California, Irvine this summer.  Gyuri made fundamental contributions to the lab’s work understanding the regulation of synaptic transmission down to the level of single dendritic spines before branching out to pioneer our in vivo studies of mouse visual cortex.  We …

Kacey wins a postdoctoral fellowship!

Postdoctoral associate Kacey Rajkovich was awarded a prestigious Yale Brown-Coxe Fellowship for her work studying the role of GABAergic inhibition in circuit organization and visual processing within mouse cortex!  Her work is allowing us to continue making connections between synapses and circuit function.

Welcome to the new Higley Lab site!

Welcome to the new Higley Lab website! Check out this space for lab news and our thoughts on goings-on in the neuroscience world! In the meantime, enjoy the awesome art work from our friend Serena Scapagnini!